Animal Health


Farming in the highlands of Ethiopia

Farming scene in the highlands of Ethiopia (photo credit: ILRI/Apollo Habtamu).

 

Zoonotic diseases, or zoonoses, are diseases that can be passed from animals to people. Nearly two-thirds of emerging infectious diseases affecting people are zoonotic and about 60% of all human pathogens are zoonotic.

Zoonoses such as brucellosis, anthrax and rabies are endemic in eastern Africa and yet formally published research studies on zoonoses in the region are hard to come by; useful research findings remain tucked away in the libraries of universities and other research institutions in form of working papers and students’ theses: the so-called ‘grey literature’.

In order to bring to the fore the wealth of unpublished research on zoonoses from studies carried out in Burundi, the Democratic Republic of the Congo, Ethiopia, Kenya, Rwanda, South Sudan, Tanzania and Uganda, the first-ever regional conference on zoonotic diseases in eastern Africa was held in Naivasha, Kenya on 9-12 March 2015.

The conference brought together academicians, researchers and graduate students from across Africa who presented on topics such as the One Health approach to disease prevention and control, the global health security agenda, the recent Ebola outbreak and its control, and control of rabies in East Africa.

Some 80 oral and poster presentations covered a wide range of aspects of research on zoonotic diseases including epidemiology, antimicrobial resistance, diagnosis, surveillance, outbreak investigations, disease modelling and foodborne zoonoses.

Bernard Bett, a veterinary epidemiologist at the International Livestock Research Institute (ILRI), gave a keynote presentation on behalf of the institute’s director general Jimmy Smith detailing how research by ILRI is contributing towards healthy people, animals and ecosystems.

Food insecurity remains a challenge for millions of people in the region. Animal-source foods can play a role in improving food and nutritional security, particularly in developing countries where demand for meat, milk and eggs is on the rise. Thus, food security is linked to the health of the livestock that produce these food products.

However, because of the threat of endemic and emerging zoonotic diseases, human health is influenced by animal health. Furthermore, changing patterns of land use, such as irrigation and intensified farming, can have an impact on the life cycles of vectors that spread diseases that affect both animals and people. Therefore, the impact of agriculture on ecosystem health also needs to be considered when tackling animal and human health challenges.

View the presentation “Healthy people, animals and ecosystems: The role of CGIAR research
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The contribution of livestock to human and animal health was among the several topics discussed at a high-profile conference organized by the International Livestock Research Institute (ILRI) in Addis Ababa, Ethiopia on 6-7 November 2014. The theme of the conference was Livestock-based options for sustainable food and nutritional security, economic well-being and healthy lives.

The conference was the culmination of a series of events organized this year to mark 40 years of livestock research by ILRI and its predecessors, the International Laboratory for Research on Animal Diseases (ILRAD) and the International Livestock Centre for Africa (ILCA).

Discussions under the sub-theme of ‘livestock and healthy lives’ began on the morning of the first day of the conference with a featured talk by Lorne Babiuk, vice president for research at the University of Alberta on how healthy animals can improve the health, welfare and economy of people.

Lorne Babiuk, vice-president for research at the University of Alberta

Lorne Babiuk presents a featured talk titled Healthy animals equals healthy, productive people at the ILRI@40 conference held on 6-7 November 2014 in Addis Ababa, Ethiopia (photo credit: ILRI/Apollo Habtamu).

In his presentation, Babiuk noted that smallholder farmers dominate livestock production in many developing countries and globally, one billion poor people depend on livestock for their livelihoods.

However, despite the potential of smallholder livestock production to contribute to meeting the growing demand for animal protein in the developing world, the livestock sector is beset by several challenges such as emerging diseases and limited natural resources for raising livestock.

Zoonotic diseases, in particular, have impacts on international trade, food prices and human health.

Babiuk then discussed three biotechnology options that can be used to improve livestock production: vaccines, breeding and selection of disease-resistant animals, and marker-assisted management to produce better quality carcasses.

“Vaccination, in my opinion, has been one of the most cost-effective approaches for the management of infectious diseases,” he said.

“In fact, it’s been stated that vaccination has saved more lives than all other therapeutic interventions in the world.”

He also gave examples of how genetics can be used to improve productivity through classical breeding and selection and use of genomic tools.

Babiuk summed up his presentation by stating that increasing food security will become more critical as the world population increases and that “healthy animals equals healthy people equals healthy environment equals stable economic environments”.

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Continuing with the underlying theme of Babiuk’s talk, a roundtable discussion was held in the afternoon to examine the relationship between livestock, nutrition and health.

John McDermott, director of the CGIAR Research Program on Agriculture for Nutrition and Health, moderated the discussion. The panellists were Walter Masiga, the World Organisation for Animal Health sub-regional representative for eastern Africa; Juliana Rwelamira, managing director of Sasakawa Africa Association and Vish Nene, director of ILRI’s livestock vaccines initiative.

Vish Nene, Juliana Rwelamira and Walter Masiga, panelists at ILRI@40 roundtable discussion on livestock and healthy lives

Left to Right: Vish Nene (ILRI), Juliana Rwelamira (Sasakawa Africa Association) and Walter Masiga (World Organisation for Animal Health) take part in a roundtable discussion on livestock and healthy lives at the ILRI@40 Addis Ababa conference (photo credit: ILRI/Apollo Habtamu).

McDermott began with an overview of the controversial and somewhat counterintuitive role of livestock in nutrition.

He noted that while animal-source foods are important sources of nutrition for poor people in low-income countries, there is underconsumption of livestock products by the poor on account of the high price of meat, milk and eggs relative to that of cereals.

On the other hand, overconsumption of livestock products in high-and middle-income countries has led to an increase in cases of obesity and related non-communicable diseases, a trend that is starting to emerge in low-income countries as well.

McDermott also noted that while meat, milk and eggs are good sources of vital nutrients, there are considerable health risks associated with livestock and livestock products.

“The most nutritious foods are also the most risky. You’re not going to get very sick eating rice as compared to eating spoiled milk or meat,” he said.

Intensification of agriculture to increase the supply of livestock is also associated with environmental contamination and increase of microbial populations, he added, noting that three-quarters of emerging diseases are zoonotic.

The roundtable discussion sought to link the economic development agenda of the livestock sector with issues related to health and nutrition.

Among the topics discussed were the One Health approach for more effective control of emerging diseases; vaccines and diagnostics; value chain development to reduce postharvest food losses and improve food safety and nutritional quality; risk-based approaches to food safety in informal markets and strengthening of national control systems to prevent misuse of antibiotics in treatment of animals.

The outcomes of the discussions on livestock and health on the first day of the conference fed into a parallel session on the second day. The aim of the session was to look into the future to identify the key priority areas for research on livestock and health in the next 40 years.

About 20 participants, mostly veterinary practitioners, took part in the parallel session on livestock and healthy lives which began with three scene-setting PowerPoint presentations and one poster presentation by scientists from ILRI’s Food Safety and Zoonoses program:

Following the presentations, the participants split into three groups for an in-depth discussion of the identified priority areas for research on livestock and health in the next 40 years. The discussions were based on their individual experiences, the content of the three presentations and current global trends in animal and human health.

They identified the following three priority areas for research on livestock and health:

  • emerging infectious diseases;
  • vaccines and diagnostics; and
  • antimicrobial residues and resistance.

Research on emerging infectious diseases needs to focus on increased understanding of the drivers of disease, for example, agricultural intensification, climate change, new farming systems, irrigation and increased mobility of animals and people. Research activities could include mapping, modelling and analysis of vectors; vector control through the use of ‘green’ insecticides; biological control of vectors and adoption of the Ecohealth approach to disease prevention and control.

Research on vaccines should be aimed at developing safe, single-dose, affordable ‘combination’ vaccines that are easy to deliver and target multiple pathogens. Rapid diagnostics that can be used along the food chain and are linked into large databases for surveillance can provide early warning systems for quick detection and reporting of potential health hazards and timely intervention.

Research on antibiotic residues and resistance needs to ensure prudent use of antimicrobials for treatment of farm animals to avoid residues in animal-source food products. The transfer of antibiotic resistance from animals to milk, meat and eggs was also identified as an important research area.

Dieter Schillinger

Dieter Schillinger leads a group discussion on antimicrobial residues and resistance as a priority area for research on livestock and healthy lives (photo credit: ILRI/Apollo Habtamu).

The group summed up the vision of ILRI’s livestock-for-health research in the next 40 years as follows:

ILRI research has contributed to appropriate health management systems leading to healthy animals, people and ecosystems and increase animal-source food and income for all’.

ILRI Clippings

Sierra Leone: into the Ebola epicentre

The district of Kailahun, in eastern Sierra Leone, bordering Guinea, is home to this 88-bed largest Ebola treatment and isolation centre set up by Médecins Sans Frontières (photo on Flickr by ©EC/ECHO/Cyprien Fabre).

This opinion piece is written by Eliza Smith

‘By now, it seems we’ve heard everything there is to hear about the mysterious bloody disease called Ebola: heartbreaking tales of loss and heroism, news of ground-breaking science to find a cure, reports of panic and much misinformation.

‘But there are three simple, if unpalatable, truths that we aren’t hearing enough about.

‘First, this is not a particularly mysterious disease.

‘It’s one of many haemorrhagic fevers caused by well-researched RNA viruses, including Lassa, Crimean-Congo haemorrhagic, dengue (‘break bone’) and yellow (jungle) fevers. All of them can cause similar symptoms in humans: fever, increased tendency to bleed and often death.

Ebola Virus

Scanning electron micrograph of Ebola virus budding from the surface…

View original post 580 more words

 

Annie Cook is a graduate fellow at the International Livestock Research Institute in Kenya. In this blog post she describes a day in the life of her PhD project.

“I am a veterinary epidemiologist which means I investigate the behaviour of diseases in animal populations. I am particularly interested in zoonoses: diseases that pass from animals to people.”

“The research project I am conducting was requested by the community. During a previous study that looked at zoonotic diseases in pigs at slaughter, our research group was asked to develop a project examining disease in the workers themselves. The workers wanted to know the occupational risks they faced at work.”

Read the full post on the CGIAR Development Dialogues blog

Delia Grace in ILRI's Guwahati office

Delia Grace, veterinary epidemiologist at the International Livestock Research Institute (photo credit: ILRI/Susan MacMillan).

We are pleased to congratulate Delia Grace on being announced as the winner of the British Veterinary Association’s (BVA) Trevor Blackburn Award in recognition of her multiple outstanding contributions to animal health, animal welfare and food safety in Africa and Asia.

In particular, she was recognized for her work with community health programs and research into public health and food safety; her pioneering work highlighting the benefits and risks of the engagement of women in livestock farming in developing countries; and the delivery of training and studies in numerous African countries.

The announcement was made today, 25 September 2014, during the awards ceremony at the BVA Members’ Day in Manchester, United Kingdom.

Grace is a veterinary epidemiologist with nearly 20 years’ experience in developing countries. She leads the Food Safety and Zoonoses program at the International Livestock Research Institute (ILRI) and the Agriculture-Associated Diseases theme of the CGIAR Research Program on Agriculture for Nutrition and Health (A4NH).

She has previously worked in various capacities and settings including general practice in Lancashire; voluntary service in rural Bangladesh; exploring the roles of community animal health systems in eastern Africa; undertaking applied research addressing the enormity of trypanosomiasis control in West Africa; advising the World Health Organization and high-level policy engagement at national and regional levels in Africa and Asia.

On learning that she was to receive the Trevor Blackburn Award for 2014, Grace commented:

“I am delighted to receive this award. I have been working since 1995 on animal health problems and their solutions in different countries of Africa and Asia.

“Around one billion poor people depend on livestock for their livelihoods and livestock disease is one of their greatest concerns and constraints. As much as a third of the value of livestock is lost each year from largely preventable diseases.

“British and Irish veterinarians have had a long history of working overseas to improve animal health and I am proud to be part of this tradition.”

Iain Wright, ILRI’s interim deputy director general, also expressed his delight upon hearing the good news.

He said: “Delia is recognized as a global leader in research on food safety and zoonoses in developing countries and is a strong supporter of the ‘One Health’ approach.”

“Having worked with community animal health care workers, she appreciates the realities of delivering animal health care services on the ground and brings this experience to bear in ensuring that her research is practical and relevant.”

The Trevor Blackburn Award recognizes contributions to animal health and welfare in a developing country by BVA members and was set up in memory of Trevor Blackburn who was president of the BVA 1984 to 1985, Commonwealth Veterinary Association 1988 to 1991 and World Veterinary Association 1991 to 1995.

View some of Delia Grace’s research publications here

Pastoralism is a farming system practised in arid and semi arid lands by societies that derive most of their food and income from livestock production. About 70% of the land mass in the Horn of Africa is dry land. In Kenya 80% of the land mass is classified as arid and semi-arid while approximately half of Tanzania consists of dry land. These dry lands can only be effectively used for livestock rearing, supporting wildlife resource harvesting and tourism.

The poster below, prepared for the Tropentag 2014 conference, presents findings of a situation analysis of animal health and its implication on food safety in Kenya and Tanzania. The study reports on livestock diseases with high prevalence and their likely effects on food safety and food security in pastoral communities in the two countries. The extent of species rearing diversification, pastoralist trade orientation and practices that may expose the community and their trading partners to animal and zoonotic infections are also explained.

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Pastoralism: Animal health and food safety situation analysis, Kenya and Tanzania

This week, ILRI staff are participating in the Tropentag 2014 International Conference in Prague, Czech Republic (17-19 September 2014). There is also a dedicated ILRI@40 side event on livestock-based options for sustainable food and nutritional security and healthy lives.  See all the posters.

ILRI news

Northeastern Kenya 17

Part of a large camel herd in northern Kenya; on the outskirts of Marsabit and Moyale, the average distances to watering points run into dozens of kilometres (photo credit: Ann Weru/IRIN).

Written by Dan Klotz

Two new papers on MERS coronavirus and camels in Eastern Africa have been published in the science journal Emerging Infectious Diseases.

Summary points

  • Studies find that camels in Egypt, Kenya, Somalia and Sudan have antibodies to the coronavirus that causes MERS.
  • The first study indicates that young camels are at greater risk of harbouring the virus than older camels.
  • We do not know if the infections in East African camels have led to, or could lead to, disease in people; this possibility should be investigated.
  • We do not know if or how much the East African camel virus is related to the one infecting camels and people in the Arabian Peninsula and Egypt; this possibility…

View original post 976 more words

Emerging and neglected zoonoses have often been managed sectorally, but recent decades have shown, in case after case, the benefits of One Health management.

The growing body of evidence suggests the time has come to make the bigger case for massive investment in One Health to transform the management of neglected and emerging zoonoses, annually saving the lives of millions of people as well as hundreds of millions of animals whose production supports and nourishes billions of impoverished people.

Delia Grace, a veterinary epidemiologist and food safety expert at the International Livestock Research Institute (ILRI) sets out a ‘Big 5’ framework for One Health:

  1. Join up health resources: Share health resources across human and veterinary sectors
  2. Control zoonoses in animal reservoirs
  3. Detect disease outbreaks early
  4. Prevent pandemics
  5. Add value to health research and development

Read the full post on the CGIAR Development Dialogues blog

Read an earlier full version of this story on the ILRI News blog

ILRI Asia

'One Health' seminar in Philippines: Participants

ILRI’s Fred Unger (back row with glasses) and Jackie Escarcha (second left, front row) with the Philippine Council for Agriculture, Aquatic and Natural Resources Research and Development team and other participants of an ‘ecohealth’ and ‘one health’ seminar held in Pampanga, Philippines in July 2014 (photo credit: ILRI).

On 30-31 July 2014, Fred Unger, a veterinary epidemiologist and Centre for International Migration and Development (CIM) expert with the International Livestock Research Institute (ILRI), visited the Philippine Council for Agriculture, Aquatic and Natural Resources Research and Development (PCAARRD) project site in Pampanga, Philippines and served as a resource speaker for a ‘seminar on ecohealth and one health: An introduction. Unger was accompanied, at the seminar, by Jackie Escarcha from ILRI’s office in Los Banos.

The PCAARRD project, represented by Edwin Villar, the director for livestock division, held the introductory seminar for the project team to gain basic understanding of ‘ecohealth’ and ‘one health’ approaches…

View original post 146 more words

ILRI Clippings

Feeding poultry, Bangladesh. Photo by WorldFish, 2006

Feeding poultry in Bangladesh (photo on Flickr by WorldFish).

A recent paper that maps the global distributions of the world’s major livestock species has already been used to advance understanding of where surveillance efforts should be targeted to prevent the possible spread of a lethal bird flu virus now circulating in poultry populations in China, where it has killed 62 people. The original mapping work, led by Tim Robinson, of the International Livestock Research Institute (ILRI), and published at the end of May, was immediately put to practical use in locating large regions in South and Southeast Asia that would suit the new lethal virus. Ominously, unlike H5N1, a viral strain of bird flu that has killed millions of poultry and at least 359 humans since its first appearance in 1987, H7N9 does not cause severe illness in the chickens it infects, making it much more difficult to detect, and…

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