Emerging Diseases


Smallholder pig production in northern Viet Nam

Farmer Ma Thi Puong feeds her pigs on her farm near the northern town of Mieu Vac, Vietnam (photo credit: ILRI/Stevie Mann).

One Health is an interdisciplinary approach to combating emerging infectious diseases by addressing the complex interactions of human health, animal health and the environment.

The One Health approach encourages the collaborative efforts of multiple disciplines working locally, nationally, regionally and globally to attain optimal health for people, animals and the environment.

Seventy-five per cent of all new, emerging or re-emerging diseases affecting humans at the beginning of the 21st century originated in animals.These zoonotic diseases present serious public health, economic and development challenges.

The subject of One Health took centre stage during the August 2013 International Symposium of Health Sciences (i-SIHAT 2013) held in Kuala Lumpur, Malaysia.

In a keynote presentation at the start of the symposium, Hung-Nguyen Viet – a researcher at the Center for Public Health and Ecosystem Research (CENPHER) at the Hanoi School of Public Health who is on a joint appointment at the International Livestock Research Institute (ILRI) – discussed a regional One Health initiative in Southeast Asia and how this integrated approach is working to develop the capacity of universities to respond to the threat of emerging infectious diseases.

View the presentation, One Health – an interdisciplinary approach in combating emerging diseases

A new 3-minute video presents an overview of the work that the International Livestock Research Institute (ILRI) is doing towards the prevention and control of agriculture-associated diseases.

This is one of the key themes of the CGIAR Research Program on Agriculture for Nutrition and Health, which is led by the International Food Policy Research Institute (IFPRI).

This CGIAR Research Program was started in 2012 to investigate the links between agriculture, nutrition and health in poor nations.

The program aims at improving the nutritional and health benefits of the farming sector while mitigating the risks posed by diseases that are spread through food and water, as well as those that can be passed from animals to people (zoonotic diseases).

In addition to a focus on agriculture-associated diseases, it also carries out research on food value chains, biofortification, and integrated development policies and programs on agriculture, nutrition and health.

View the video, The prevention and control of agriculture-associated diseases

The prevention and control of agriculture-associated diseases from FILM for SCIENCE in AGRICULTURE on Vimeo.

You are welcome to share this video with research colleagues and partners or embed it in your PowerPoint/Prezi presentations on agriculture, nutrition, health and food safety.

Smallholder pig production in northern Viet Nam

Farmer Ma Thi Puong feeds her pigs on her farm near the northern town of Meo Vac, Vietnam. Intensification of livestock farming has been found to increase the risk of zoonotic disease transmission (photo credit: ILRI/Stevie Mann).

Modern farming practices, such as intensified livestock production, as well as environmental and biodiversity changes can be linked to the new wave of zoonotic diseases, according to a new study published in the 21 May 2013 edition of the Proceedings of the National Academy of Sciences (PNAS).

Human population growth and the expansion of agriculture to meet the ever-rising demand for food have been identified as the key drivers of recent outbreaks of emerging and re-emerging zoonotic diseases.

These human behavioural changes have led to encroachment of wildlife habitats, resulting in greater interactions between people, livestock and wildlife and increased chances of spillover of potential pathogens from wildlife to livestock and, consequently, people.

“Intensive livestock farming, especially of pigs and poultry, increases the risk of disease transmission due to increased population size and density,” the study reveals.

Environmental changes arising from settlement and agriculture, including land fragmentation, deforestation and replacement of natural vegetation with crops, alter the structure of wildlife population, giving rise to new environmental conditions that favour specific hosts, vectors and pathogens.

The study was carried out in form of a systematic review by a multidisciplinary team of researchers from the International Livestock Research Institute (ILRI) and the Royal Veterinary College, University of London.

The research team sought to analyze qualitatively scientific evidence on the effect of agricultural intensification and environmental change on the risk of zoonoses transmission at the interface of humans, livestock and wildlife.

While the study has identified a clear link between the threat of zoonotic disease and the wildlife-livestock interface, it does not adequately address the complex interactions between the environmental, social and biological drivers of pathogen emergence.

For this reason, there is need to carry out local interdisciplinary studies that can come up with locally relevant solutions to tackle the threat of emerging and re-emerging zoonoses, the authors conclude.

Delia Grace, veterinary epidemiologist and food safety expert at ILRI, is among the co-authors of the study. Grace also leads the agriculture-associated diseases theme of the CGIAR Research Program on Agriculture for Nutrition and Health.

Read the full-text article

Citation: Jones BA, Grace D, Kock R, Alonso S, Rushton J, Said MY, McKeever D, Mutua F, Young J, McDermott J and Pfeiffer DU. 2013. Zoonosis emergence linked to agricultural intensification and environmental change. Proceedings of the National Academy of Sciences of the United States of America (PNAS) 110(21): 8399-8404.

Live chicken vendor in Vietnam

A live chicken vendor weighs a chicken in Hung Yen province, Vietnam (photo credit: ILRI/Nguyen Ngoc Huyen).

The experiences of the International Livestock Research Institute (ILRI) in using One Health and EcoHealth approaches to better manage emerging zoonoses were featured during a poster session at the 2013 Prince Mahidol Award Conference that was held in Bangkok, Thailand from 29 January to 2 February 2013. The theme of the conference was: “A world united against infectious diseases: Cross-sectoral solutions”.

ILRI scientists Jeffrey Gilbert and Rainer Assé presented two research posters from the project, Ecosystem approaches to the better management of zoonotic emerging infectious diseases in the Southeast Asia Region.

The project works with trans-disciplinary teams from governments, non-governmental organizations and universities in Cambodia, China, Indonesia, Laos, Thailand and Vietnam to increase the capacity of researchers and animal disease control personnel to understand the risks and impacts of zoonotic emerging infectious diseases and best practice options to better manage the diseases.

View the posters below.

The added value of an ecohealth approach for the prevention and control of emerging zoonotic diseases by Jeffrey Gilbert

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Examining the socioecology of zoonotic diseases: Ecohealth experiences in Southeast Asia by Rainer Assé, Korapin Tohtubtiang, Jeffrey Gilbert and Delia Grace

Maasai father and son tend to their cattle in Kenya

Maasai father and son tend to their cattle in their paddock in Kitengela, Kenya (photo credit: ILRI/Stevie Mann).

Brucellosis, also referred to as undulant fever, is a highly contagious zoonotic disease caused by the microorganism Brucella which infects multiple animal species including cattle, sheep, pigs, small ruminants, camels, water buffaloes and yaks.

Brucellosis affects both humans and animals, causing chronic fever and joint and muscle pain in humans and abortion in animals.

Cases of brucellosis in humans are often linked to consumption of unpasteurized milk and soft cheese made from the milk of infected cows.

Brucella infection in some developing countries can reach 30% of the human population, making it a serious public health disease.

In response to the problem of this disease in Africa, some 60 animal health experts from across Africa, the United States and other countries gather in Addis Ababa, Ethiopia from 29 to 31 January 2013 for a workshop to discuss an integrated approach to controlling brucellosis.

The workshop aims to identify gaps in brucellosis epidemiology, diagnosis, surveillance and control programs.

This will assist in designing research programs and intervention strategies to aid in the control of brucellosis at national and regional levels.

Specific topics that will be addressed include:

  • Transmission of infection from animals to humans
  • Laboratory biosafety practices
  • Diagnostics assays, serology and organism identification
  • Vaccination strategies
  • Potential research collaborations

The workshop is co-organized by the Agricultural Research Service of the United States Department of Agriculture (USDA-ARS), the International Livestock Research Institute (ILRI) and the United States Agency for International Development (USAID).

It is sponsored by the US Department of State Biosecurity Engagement Program.

ILRI scientists Delia Grace, Eric Fèvre and Roger Pellé will attend the workshop.

Additional information is available on the USDA-ARS website

Typical mixed crop-livestock farming in western Kenya

Typical mixed crop-livestock farming in western Kenya. Mixed crop-livestock farming systems currently produce most of the world’s meat, milk and staple crops (photo credit: ILRI/Pye-Smith).

The January 2013 issue of Animal Frontiers, the world’s premier review magazine in animal agriculture, features a series of articles on the contribution of animal agriculture to global food security.

The International Livestock Research Institute (ILRI) has contributed to this series with a position paper that highlights the direct and indirect effects of livestock on food and nutrition security. The paper also considers the future prospects of mixed crop-livestock farming systems that produce most of the world’s milk, meat and staple crops.

The paper by ILRI director general Jimmy Smith and colleagues begins with a brief overview of the global challenge of food and nutrition security and the net impact of livestock on global food supply. This is followed by a review of the direct contributions of livestock to nutrition security and the indirect effects of livestock on food security.

Food security is said to exist when “all people at all times have access to sufficient, safe, nutritious food to maintain a healthy and active life”. In development discourse, the term ‘food security’ is often used to emphasize the aspect of food quantity while ‘nutrition security’ captures the quality dimension.

The position paper offers a balanced analysis by exploring both the beneficial impacts (e.g. improved nutrition and health, income from the sale of animals or produce, draught power and provision of manure) and the harmful ones (e.g. zoonotic diseases, health risks from over-consumption of animal-source foods and production of greenhouse gases).

“Livestock contribute to food supply by converting low-value materials, inedible or unpalatable for people, into milk, meat, and eggs; livestock also decrease food supply by competing with people for food, especially grains fed to pigs and poultry. Currently, livestock supply 13% of energy to the world’s diet but consume one-half the world’s production of grains to do so.

However, livestock directly contribute to nutrition security. Milk, meat and eggs, the “animal-source foods,” though expensive sources of energy, are one of the best sources of high quality protein and micronutrients that are essential for normal development and good health. But poor people tend to sell rather than consume the animal-source foods that they produce.

The contribution of livestock to food, distinguished from nutrition security among the poor, is mostly indirect: sales of animals or produce, demand for which is rapidly growing, can provide cash for the purchase of staple foods, and provision of manure, draft power, and income for purchase of farm inputs can boost sustainable crop production in mixed crop-livestock systems.

Livestock have the potential to be transformative: by enhancing food and nutrition security, and providing income to pay for education and other needs, livestock can enable poor children to develop into healthy, well-educated, productive adults. The challenge is how to manage complex trade-offs to enable livestock’s positive impacts to be realized while minimizing and mitigating negative ones, including threats to the health of people and the environment.”

On the future role of mixed crop-livestock farming systems, the authors note that it is important to look into issues related to production efficiency as well as market engagement in defining how these systems are to evolve in order to remain competitive, equitable and environmentally stable while continuing to contribute to human nutrition and health.

The paper concludes:

“Many poor livestock keepers report that a key motivation for keeping livestock is to earn income so their children can attend school and, perhaps, go on to benefit from further education. By providing essential nutrients, especially in the first critical 1,000 days from conception, animal-source foods can help ensure normal physical and cognitive development.

The combined impacts of meeting nutritional needs and providing income make livestock a powerful force for the poor. Well-nourished and well-educated youngsters can grow up to be healthy young adults who are able to realize their full potential and earn higher incomes, in the process enhancing the well-being of their families, communities, and society. The impact of this on food and nutrition security at household, national, and global levels cannot be overstated and demands innovative research, development, and policy approaches.”

Read the full article here

Citation: Smith J, Sones K, Grace D, MacMillan S, Tarawali S and Herrero M. 2013. Beyond milk, meat, and eggs: Role of livestock in food and nutrition security. Animal Frontiers 3(1): 6-13.

The Lancet has launched a new three-part series on zoonotic diseases (diseases that are transmissible between animals and people).

“Zoonoses – pathogenic organisms such as bacteria or viruses which we share with animals – cause more than 60% of human infectious diseases, and have been responsible for some of the most devastating disease outbreaks in recent years, including HIV, Ebola, and SARS.

However, despite their huge, and rising, impact on human health, there are still huge gaps in our understanding of how zoonoses spread and develop, which need to be urgently addressed if we are to be able to reduce the impact of the next zoonotic pandemic.

In a new Lancet series, leading experts discuss the ecology, drivers and dynamics of zoonoses, while also addressing how we might predict the next zoonotic pandemic, and reduce the potentially catastrophic human and economic cost of such an outbreak.”

Read the full-text series papers here

14th International Conference of the Association of Institutes for Tropical Veterinary Medicine

The first announcement and call for abstracts has been issued for the 14th International Conference of the Association of Institutes for Tropical Veterinary Medicine, to be held on 25–29 August 2013 at the Indaba Hotel and Conference Centre, Johannesburg, South Africa.

The theme is: “The livestock-human-wildlife interface” – Challenges in animal health and production in urban and extensive farming/conservation systems.

The conference is jointly organised by the University of Pretoria and the Institute of Tropical Medicine Antwerp.

The scientific program consists of the following six themes:

  • Diagnosis, surveillance and control at the interface
  • Drivers of emerging and re-emerging diseases (with particular reference to zoonoses)
  • Animal welfare at the interface
  • Food safety and food security (including marketing and trade)
  • Training opportunities in the context of the interface
  • Animal health and production

The deadline for submission of abstracts is Friday 15 February 2013. Abstracts are to be submitted electronically at http://www.easyabstract.com

Online registration for the conference will open on 1 February 2013 on the website, http://www.aitvm2013.org

Download the conference announcement

ILRI Clippings

Tamiflu

A CNN report this week on ‘The looming zoonotic danger’ makes use of some astounding figures developed by veterinary epidemiologist Delia Grace and her team at the International Livestock Research Institute (ILRI), based in Kenya.

‘We’ve seen an unprecedented rise in infectious diseases in recent decades, 75 percent of which are “zoonotic,” meaning they come from animals. About 300 new animal-to-human diseases have emerged in the last 60 years.

This summer, the International Livestock Research Institute released a report estimating that zoonotic diseases cause 2.5 billion cases of human illness each year and 2.7 million human deaths worldwide. Most of these illnesses and deaths are caused by diseases spread from farm animals. . . .

‘New chicken and pig flu viruses have emerged at an alarming rate in recent decades. The latest swine flu virus, dubbed H3N2v, claimed its first human victim last month in Ohio. Up until the 1990s…

View original post 316 more words

Boran cattle at Kapiti ranch in Kenya

Boran cattle grazing at Kapiti ranch in Kenya. The Zoonotic Disease Unit in Kenya will use One Health approaches to improve prevention and control of zoonoses (photo credit: ILRI).

The One Health approach for the prevention and control of zoonotic diseases (diseases transmitted between animals and humans) was institutionalized in Kenya following the official launch of the country’s Zoonotic Disease Unit in Nairobi on 3 October 2012.

The occasion also featured the launch of the strategic plan for the implementation of One Health in Kenya. The strategic plan has the following three goals:

  • To strengthen surveillance, prevention and control of zoonoses in both humans and animals
  • To establish structures and partnerships that promote One Health approaches
  • To conduct applied research at the human-animal-ecosystem interface in order to better understand the mechanism of maintenance and transmission of zoonotic pathogens

The Zoonotic Disease Unit is the first of its kind in Africa and will serve as a model for the region in implementing innovative and integrated approaches to investigate outbreaks of zoonoses towards improved disease surveillance, prevention and control.

The Unit was set up in 2011 by the Ministry of Livestock Development and the Ministry of Public Health and Sanitation with the main objective of establishing and maintaining active collaboration at the animal, human and ecosystem interface towards better prevention and control of zoonotic diseases.

The United States Department of State Biosecurity Engagement Program, the United States Department of Defense and the Centers for Disease Control and Prevention supported the Government of Kenya in the establishment of the Zoonotic Diseases Unit.

The implementing partners include the African Union – Interafrican Bureau for Animal Resources (AU-IBAR), the Food and Agriculture Organization of the United Nations (FAO), the International Livestock Research Institute (ILRI), the Kenya Medical Research Institute (KEMRI), the Kenya Wildlife Service (KWS), the World Health Organization (WHO) and the World Organization for Animal Health (OIE).

For more information, please visit the website of the Zoonotic Disease Unit at http://zdukenya.org.

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