Food Safety


Sinh Dang Xuan defends his Master of Veterinary Public Health thesis at Chiang Mai University, Thailand

Sinh Dang Xuan defends his Master of Veterinary Public Health thesis at the Chiang Mai University, Thailand. His research study was co-funded by the ILRI-led project “Ecosystem approaches to the better management of zoonotic emerging infectious diseases in Southeast Asia” (photo credit: ILRI/Fred Unger).

Congratulations are due to Sinh Dang Xuan on the successful defence of his Master of Veterinary Public Health thesis on 9 September 2013 at the Veterinary Public Health Centre for Asia Pacific, Chiang Mai University in Thailand. The course is a joint program of Freie Universität Berlin and Chiang Mai University.

His research study on quantifying Salmonella spp. in pig slaughterhouses and pork markets associated with human health in Hung Yen, Vietnam was co-funded by a project led by the International Livestock Research Institute (ILRI) on ecohealth approaches to managing zoonoses in Southeast Asia.

It is one of the first studies carried out in Vietnam combining quantitative and qualitative research methods on ecohealth approaches to food safety in pork value chains.

View the presentation

Moses Osiru pitches his integrated approach to aflatoxins

On 23 and 24 September, the CGIAR Science Forum 2013 on ‘Nutrition and health outcomes: targets for agricultural research’ featured a parallel session on food safety.

It was organized by Delia Grace from the International Livestock Research Institute as part of the CGIAR Research Program on Agriculture for Nutrition and Health (A4NH)

Delia opened the session arguing the case for agricultural interventions for food safety.

The session drew on examples of aflatoxin control as an example of agriculture-based interventions for human health.

Five speakers ‘pitched’ their research initiatives to a panel representing investors and the audience. The pitches led in to a discussion on priorities to achieve health outcomes through research on food safety.

Poisons produced by fungi

IITA’s Fen Beed introduced participants to aflatoxins – poisons produced by Aspergillus species and infecting crops like maize, groundnut, nuts, spices and many others.  Depending on the degree of contamination in food and feed, they cause death, cancer, immuno-suppression and stunting of children. They are passed from mothers to babies; and from feed to milk. Due to the risks to human and animal health, international trade strictly regulates contamination levels of products that may be affected by aflatoxins. Mitigation of aflatoxins is therefore both a food safety and a market access issue.

Five mitigation approaches

The aflatoxin challenge was used as a focus to bring together and assess 5 current approaches to mitigation:

  • Breeding aflatoxin-resistant maize: George Mahuku, CIMMYT
  • Biological control of aflatoxins: Peter Cotty, University of Arizona
  • Integrated management of aflatoxins in maize and groundnuts: Ranajit Bandyopadhyay, IITA
  • Genetic enhancement of groundnuts to resist aflatoxins, Hari Upadhyaya: ICRISAT
  • Integrated groundnut aflatoxin management:  Moses Osiru, ICRISAT

The role of research investors was taken by Laurian Unnevehr (IFPRI), Tom Randolph (Livestock and Fish research program) and Wycliffe Kumwenda (National Smallholder Farmers’ Association of Malawi). The panelists challenged the presenters on the science and potential large scale impact of their approaches. As part of the exercise, the investor panel and the audience ‘invested’ token funds in each initiative as a device to surface different perspectives. After the counting, the investment portfolio of the panel was quite different to that of the audience.

Tom Randolph: “The investors were attracted most to the two integrated control programs, one rolling out a generic control program across crops and across Africa, and the other supporting improved control for groundnuts in southern Africa. These demonstrated thoughtful attention to a mix of control strategies and the incentives that will be needed to ensure uptake and sustained provision and use by focusing on enabling policies and partnership with the private sector. The investors didn’t ignore the other research efforts, however! They also invested in further development of the control technologies themselves: biocontrol and breeding for aflatoxin resistance in maize and groundnuts. It was recognized that investments in these efforts serve to complement those that should be demonstrating the commitment of the private sector for taking up biocontrol and the research investments in the other breeding drivers for drought resistance and yield. The session helped to underline the need to better demonstrate our potential for short term benefits while ensuring an appropriate balance of longer term discovery research.”

Reflections

Delia Grace: “With nearly one billion hungry and two billion suffering from the hidden hunger caused by micro-nutrient deficiency, there is massive interest in the role of agriculture in better feeding poor people. However, food security is not enough. The food that feeds us also sickens and kills us. Food-borne disease is the single most common disease in the world, causing around 5 billion episodes of gastrointestinal illness a year. Diarrhoea (between one third and two thirds related to food) is among the top killers of children in most poor countries. This session focused on the role of agricultural research in improving the safety of food in poor countries.

Among the important messages were:

  • Building strong links with public health, including Food Safety authorities is important;
  • Food safety in informal markets is often neglected: strong evidence on cost and benefits is needed to convince policy makers;
  • Innovations have great potential for improving food safety;
  • In informal markets and subsistence systems, we need models for effective governance;
  • CGIAR food safety research can have impact by linking with commodity and system CRPs.”

The presentations

Maize contaminated with aflatoxin

Maize contaminated with aflatoxin (photo credit: IITA).

On 22 August 2013, the Biosciences eastern and central Africa hub at the International Livestock Research Institute (ILRI) and ILRI’s Food Safety and Zoonoses program hosted a half-day seminar on the current status on aflatoxin research and management at ILRI.

The open forum was an opportunity for different working groups to engage in discussions on the ongoing and planned research projects. The seminar brought together some 30 participants and a total of 13 presentations were given on aflatoxin assessment, diagnostics, analysis and mitigation.

Aflatoxins are highly toxic metabolites produced by the mould Aspergillus flavus and known to cause suppression of the immune system, liver disease and death in both humans and animals.

Aspergillus can grow in a wide range of foods and feed and thrive under favourable growth conditions of high temperature and moisture content. Aflatoxins from contaminated animal feed can end up in milk.

Three research studies that are part of the project Measuring and mitigating the risk of mycotoxins in maize and dairy products for poor consumers in Kenya (MyDairy project) were featured during the seminar.

The goal of the MyDairy project – the fifth of seven work packages of the FoodAfrica program – is to reduce the risk of mycotoxin contamination of staple crops in Kenya.

ILRI graduate fellow Anima Sirma presented an overview of her planned PhD research on risk assessment of aflatoxins in the Kenyan dairy value chain. The objectives of the study are to characterize the key risks of aflatoxins, identify the best control options and provide risk managers with information for decision-making.

Daniel Senerwa, another ILRI graduate fellow working towards a PhD, presented his proposed research that seeks to quantify the economic costs of aflatoxins in the Kenyan dairy value chain and examine the cost effectiveness of mitigation strategies.

Sirma and Senerwa are veterinary scientists and are undertaking their PhD studies at the University of Nairobi’s Faculty of Veterinary Sciences.

Sara Ahlberg, a dairy technologist from Finland and ILRI associate research officer, presented an overview of her work on a novel biological method to mitigate aflatoxin-induced risks in food and feed with dairy-derived proteins and peptides and lactic acid bacteria that have the ability to bind aflatoxins or inhibit the growth of mycotoxin-producing moulds.

Download the seminar report

Sale of raw milk at Port-Bouët market in Abidjan, Côte d’Ivoire

Sale of raw milk at Port-Bouët market in Abidjan, Côte d’Ivoire (photo credit: ILRI/Sylvie Mireille Kouamé-Sina).

Every day, some 652 consumers of raw milk in Abidjan, Côte d’Ivoire are exposed to the risk of gastro-intestinal infection caused by harmful milk-borne bacteria, a study has shown. The study was done under the collaborative Safe Food, Fair Food project which is led by International Livestock Research Institute (ILRI).

As is the case in most countries in sub-Saharan Africa, milk in the informal or traditional market in Côte d’Ivoire is often sold raw. Many consumers routinely boil milk before drinking it, thus eliminating the health risk presented by milk-borne pathogens. However, some choose to consume the milk raw without any form of heat treatment. Unhygienic handling and storage of milk can also compromise the quality of raw milk sold to consumers.

Sylvie Mireille Kouamé-Sina, an Ivorian researcher at the Centre Suisse de Recherches Scientifiques en Côte d’Ivoire (CSRS), led the study on bacterial risk assessment of informally marketed milk in Abidjan.

Just over half (51.6%) of sampled milk consumers in Abidjan reportedly drank their milk raw. The main disease-causing bacteria isolated from the marketed raw milk were E. coli, Enterococcus sp. and Staphylococcus aureus. These species were found in about 58% of samples of informally marketed milk.

A risk model revealed that consumers of raw milk in Abidjan have a 30% chance of drinking milk that is not microbiologically safe. For this reason, boiling of informally marketed milk is recommended as a risk-mitigation strategy against milk-borne pathogenic bacteria.

Kouamé-Sina presented these findings during a poster session at the 5th Congress of European Microbiologists (FEMS 2013) which was held on 21-25 July 2013 in Leipzig, Germany. The international conference brought together 2270 participants from 70 countries across all continents. Africa was represented by 27 participants from Côte d’Ivoire (1), Egypt (2), Nigeria (11), South Africa (12) and Tunisia (1).

Various topics on the latest advances in microbiology and biotechnology were discussed, including microbial food safety, trends in pathogen monitoring, viral ecology and evolution, new perspectives in bioenergy, and microbial interactions and climate change.

“The conference was a very interesting forum for thousands of international microbiologists from Europe and around the world to assess the current status of techniques used in microbiology,” said Kouamé-Sina.

“It was especially useful for young scientists as it allowed for interaction with leading researchers and exchange of knowledge and information on the latest advances in microbiology,” she added.

View the poster, Bacterial risk assessment of milk produced locally in Abidjan, Côte d’Ivoire

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Read more about ILRI’s research on food safety in informal markets.

Cover of special issue of Vietnam Journal of Preventive Medicine on risk assessment

The Vietnamese Journal of Preventive Medicine has published a special edition on risk assessment for health research in Vietnam. The June 2013 special edition is a compilation of over 10 original research papers on the application of risk analysis to the management of animal, human and environmental health in Vietnam. The subject of training and capacity development in health risk assessment in Vietnam is also featured.

Risk analysis is a scientific, risk-based approach to assessing the health effects and economic impacts of various hazards (for example, disease-causing microorganisms in food or chemical pollutants in water) in order to develop appropriate interventions to mitigate the health risks posed by the hazards, thus ensuring that people, animals and the environment are safe.

Risk analysis comprises three components: risk assessment, risk management and risk communication. In the developed world, risk assessment is widely applied and used as a tool for risk management, thanks to the availability and accessibility of large databases of diseases.

However, many developing countries – including Vietnam – do not have the research data and risk analysis expertise needed to be able to adequately inform policymaking on risk-based approaches to health management.

The research papers featured in the special issue provide insights into the current status of research on risk analysis in Vietnam, specifically, risk assessment of the health impacts of Salmonella, E. coli and Listeria monocytogenes in the pork value chain in Hanoi, arsenic contamination in drinking water in Hanam Province, dioxin contamination in food in Da Nang and pesticide residues in farms in Thai Binh.

The work is a result of the collaborative efforts of the Vietnamese Journal of Preventive Medicine and the Center for Public Health and Ecosystem Research (CENPHER) at the Hanoi School of Public Health (HSPH).

Among the co-authors of the research papers are Delia Grace and Lucy Lapar, scientists at the International Livestock Research Institute (ILRI), and Hung Nguyen-Viet who leads research at CENPHER-HSPH and is a joint appointee of the Swiss Tropical and Public Health Institute and ILRI.

The papers are in Vietnamese with abstracts available in English. Listed below are the titles of the papers.

  • Risk assessment and health research in Vietnam (editorial)
  • Risk assessment of Salmonella in pork in Hanoi, Vietnam
  • Food-borne hazards in a transforming pork value chain in Hanoi: Basis for future risk assessments
  • Health risk due to exposure to chlorpyrifos for farmers in Thai Binh: Probabilistic risk assessment
  • Risk assessment of arsenic contamination in tube-well drinking water in Hanam Province
  • Environmental health risk assessment of dioxin in foods in Da Nang dioxin hot spot
  • Prevalence of Salmonella contamination in pig and pork at farms and slaughterhouses in the northern provinces of Vietnam
  • Air pollution as a health issue in Hanoi, Vietnam: An opportunity for intensified research to inform public policy
  • Environmental health risk communication: Concept, principles and challenges
  • Training and research programs in health risk assessment in Vietnam
  • Task force of risk assessment for food safety in Vietnam: Linking science to policy to increase food safety and livelihood generation of the poor farmer
  • Research projects on health risk assessment implemented by the Hanoi School of Public Health

The special edition also includes news on risk assessment training in Vietnam and reviews of two books on risk assessment.

For more information on this special edition, please contact Hung Nguyen-Viet (hung.nguyen @ unibas.ch).

Beef and pork sellers in Maputo's traditional market

Traders in beef and pork meat at the Xipamanine traditional market in Maputo, Mozambique (photo credit: ILRI/Stevie Mann).

In many countries of sub-Saharan Africa, informal markets play an important role in supplying most of the meat, milk, eggs and fish that poor people depend on for their nourishment.

Informal markets are those where traditional processing and products predominate and where traders are often unlicensed and do not pay tax.

Examples include street food markets, milk hawking systems, wet markets for pork, backyard poultry systems and artisanal production of cheese and other fermented milk products.

Despite the important role of Africa’s informal food markets in providing nutrition, employment and income to millions of people, these markets are often not subject to effective health and safety regulation.

Several approaches to food safety in informal markets have focused on food-borne hazards, with a tendency to adopt stringent international food quality standards with little regard for local contexts.

On the other hand, risk-based approaches to food safety do not just consider the presence or absence of food-borne hazards, but go further to assess whether there are certain practices that can minimize the health risks presented by the hazards.

Take, for example, the case of raw milk which is often sold informally in many parts of sub-Saharan Africa.

It is well known that raw milk is a good medium for microbial growth and is prone to microbial spoilage if not cooled immediately after milking.

Pathogenic species like E. coli often occur naturally in raw milk. However, most consumers in Africa routinely boil milk before they drink it, a simple practice that effectively kills any milk-borne pathogens, thus rendering the milk safe to drink.

A hazard-based approach to food safety that focuses solely on the hazard (E. coli in raw milk) would quickly condemn the milk as ‘unsafe for human consumption’.

However, a risk-based approach that considers risk assessment (E. coli is present in raw milk and causes disease), risk management (boiling of raw milk) and risk communication (educating consumers to boil milk before drinking it) is more appropriate as it is based on evidence of potential harm and not perceptions.

The subject of food safety in informal markets in Africa will be among several topics to be discussed during a side event by the International Livestock Research Institute (ILRI) on the first day of the 6th Africa Agriculture Science Week which takes place on 15-20 July 2013 in Accra, Ghana.

The topic of the ILRI side event is Livestock research for Africa’s food security.

ILRI veterinary epidemiologist and food safety expert Delia Grace will speak on the topic of food safety and aflatoxins.

Aflatoxins are highly toxic metabolites produced by the mould Aspergillus flavus and known to cause suppression of the immune system, liver disease and death in both humans and animals.

Aspergillus can grow in a wide range of foods and feed and thrive under favourable growth conditions of high temperature and moisture content.

In Africa, aflatoxin contamination of cereals, groundnuts and dried fruits leads to an estimated annual loss to food exporters of 670 million US dollars.

Grace leads ILRI’s research program on food safety and zoonoses. She also leads the ‘agriculture-associated diseases’ theme of the CGIAR Research Program on Agriculture for Nutrition and Health, led by the International Food Policy Research Institute (IFPRI).

Grace will address the following questions:

  • What are risk-based approaches to food safety in informal markets where most of the poor buy and sell?
  • How should we deal with food safety dynamics: livestock revolution, urbanization and globalization?
  • How can we better understand the public health impacts of aflatoxins?

Other topics that will be discussed at the side event are

Read more about ILRI’s food safety projects in Africa

For more information about the 6th Africa Agriculture Science Week, follow updates on the blog or the Twitter feed #AASW6.

A new 3-minute video presents an overview of the work that the International Livestock Research Institute (ILRI) is doing towards the prevention and control of agriculture-associated diseases.

This is one of the key themes of the CGIAR Research Program on Agriculture for Nutrition and Health, which is led by the International Food Policy Research Institute (IFPRI).

This CGIAR Research Program was started in 2012 to investigate the links between agriculture, nutrition and health in poor nations.

The program aims at improving the nutritional and health benefits of the farming sector while mitigating the risks posed by diseases that are spread through food and water, as well as those that can be passed from animals to people (zoonotic diseases).

In addition to a focus on agriculture-associated diseases, it also carries out research on food value chains, biofortification, and integrated development policies and programs on agriculture, nutrition and health.

View the video, The prevention and control of agriculture-associated diseases

The prevention and control of agriculture-associated diseases from FILM for SCIENCE in AGRICULTURE on Vimeo.

You are welcome to share this video with research colleagues and partners or embed it in your PowerPoint/Prezi presentations on agriculture, nutrition, health and food safety.

On 3-4 September 2012 participants from five CGIAR centres met at the International Livestock Research Institute (ILRI) in Nairobi to share about their activities related to mycotoxin research and to plan how these different activities might work together within the CGIAR Research Program on Agriculture for Nutrition and Health (A4NH) mycotoxin research portfolio.

Representatives attended from the International Maize and Wheat Improvement Center (CIMMYT), the International Crops Research Institute for the Semi-Arid Tropics (ICRISAT), the International Institute of Tropical Agriculture (IITA),  the International Food Policy Research Institute (IFPRI) and ILRI.

The meeting report is now published, highlighting the key issues, decisions and action points.

Download the meeting report.

Aflatoxin-contaminated groundnut kernels

Aflatoxin-contaminated groundnut kernels from Mozambique. The Partnership for Aflatoxin Control in Africa has identified five priority strategic areas for action towards control of aflatoxins in Africa (photo credit: IITA).

Regional and international experts in agriculture, health, research and trade have drawn up a plan of action for the control of aflatoxins in Africa, following a strategy development workshop organized by the Partnership for Aflatoxin Control in Africa held on 10-12 April 2013 in Dar es Salaam, Tanzania.

“Control of aflatoxins is needed to achieve greater agricultural development, food security and improve health, particularly in Africa where contamination is widespread and often acute,” said Yemi Akinbamijo, head of the Agriculture and Food Security Division of the African Union Commission.

The workshop participants identified five priority strategic thematic areas for action:

  • Research and technology for control of aflatoxins
  • Legislation, policies and standards in the management of aflatoxin in Africa
  • Growing commerce and trade while protecting lives from aflatoxins
  • Enhancing capacity building on aflatoxin management, control and regulatory processes to ensure reduced exposure
  • Public awareness, advocacy and communication

Aflatoxins are highly toxic metabolites produced by the mould Aspergillus flavus and known to cause suppression of the immune system, liver disease and death in both humans and animals.

Aspergillus can grow in a wide range of foods and feed and thrive under favourable growth conditions of high temperature and moisture content.

The Food and Agriculture Organization (FAO) estimates that 25% of the world’s food crops are affected by aflatoxins, with countries in the tropics and subtropics at most risk.

Aflatoxin contamination can occur before crops are harvested when temperatures are high, during harvest if wet conditions occur and after harvest if there is insect damage to the stored crop or if moisture levels are high during storage and transportation.

In Africa, aflatoxin contamination of cereals, groundnuts and dried fruits leads to an estimated annual loss to food exporters of 670 million US dollars.

Among the over 110 experts who attended the strategy development workshop were three scientists from the International Livestock Research Institute (ILRI) involved in food safety research as part of the agriculture-associated diseases component of the CGIAR Research Program in Agriculture for Nutrition and Health (A4NH).

Benoit Gnonlonfin and Jagger Harvey of the ILRI-Biosciences eastern and central Africa hub are involved in a collaborative project, Capacity and Action for Aflatoxin Reduction in Africa, aimed at establishing a regional mycotoxin analytical platform with state-of-the-art diagnostic technology that will enable better detection and control of aflatoxin contamination in maize in Kenya and Tanzania.

Delia Grace is a veterinary epidemiologist and food safety expert and leads of ILRI’s Food Safety and Zoonoses Program as well as the agriculture-associated diseases component of A4NH.

Grace is involved in the project Measuring and mitigating the risk of mycotoxins for poor milk and maize producers and consumers in Kenya (MyDairy), which aims at improving food safety through reducing the risk of mycotoxins within the feed-dairy chain in Kenya.

The key aspects of the MyDairy project are:

  • integrated risk and economic assessment of the Kenyan feed-dairy chain;
  • investigation of technologies and strategies to reduce mycotoxins risk in the feed-dairy chain; and
  • impact assessment of a package of post-harvest strategies for reducing aflatoxins in maize.

Erastus Kang’ethe, a meat and milk expert at the University of Nairobi, who also attended the workshop, is one of the partners in the MyDairy project.

Access the workshop documents and presentations

Delia Grace, food safety specialist at the International Livestock Research Institute (ILRI), is cited in this feature article on urban livestock farming and zoonoses in Dagoretti, Nairobi.

Research by Grace and colleagues found that peer pressure and targeted messages on hygienic livestock keeping work better to control the spread of cryptosporidiosis than banning the keeping of animals.

ILRI Clippings

Meat Store in Kawangware Slum

Butcher shop in a slum in Kawangare, Nairobi, Kenya (picture on Flickr by Brad Ruggles).

It’s not only people who are rapidly urbanizing in Africa: people migrating from rural areas are bringing their livelihoods with them, which in Africa largely means their cattle, goats, sheep, chickens and pigs. A scientific report from researchers based in Nairobi, Kenya, investigating the benefits and harms of livestock keeping in two of Africa’s most crowded and sprawling cities —Nairobi and Ibadan — recommends that people ‘keep on keeping cows’ but keep them more carefully so as to reduce the risk of diseases being transmitted from livestock to people.

Importantly, the study also finds that  peer pressure — not health codes — is the answer to more careful management of the growing livestock enterprises in Africa’s slums and urban centres.

The Atlantic, one of North America’s most popular and distinguished cultural and political magazines, explores this…

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