Zoonotic Diseases


Currently new diseases are emerging at the rate of one every four months and three out of four of these diseases jump species from other animals. Many of these diseases are associated with agriculture. Scientists from the International Livestock Research Institute (ILRI) led two systematic reviews of disease emergence and burden to help in prioritization. The poster below, prepared for the Tropentag 2014 conference, presents the key findings of the reviews.

.

Sustainable intensification?: Implications for the emergence of diseases

This week, ILRI staff are participating in the Tropentag 2014 International Conference in Prague, Czech Republic (17-19 September 2014). There is also a dedicated ILRI@40 side event on livestock-based options for sustainable food and nutritional security and healthy lives.  See all the posters.

The Rift Valley fever virus is a mosquito-borne pathogen that causes explosive outbreaks of severe human and livestock disease in Africa and Arabian Peninsula. The rapid evolution of outbreaks of Rift Valley fever generates exceptional challenges in its mitigation and control.

A decision-support tool for prevention and control of Rift Valley fever in the Greater Horn of Africa identifies a series of events that indicates increasing risk of an outbreak and matches interventions to each event.

This poster, prepared for the Tropentag 2014 conference, presents information from a study that assessed the effectiveness of targeted vaccination in mitigating the impacts of outbreaks of Rift Valley fever.

.

Mitigation of the impacts of Rift Valley fever through targeted vaccination strategies

This week, ILRI staff are participating in the Tropentag 2014 International Conference in Prague, Czech Republic (17-19 September 2014). There is also a dedicated ILRI@40 side event on livestock-based options for sustainable food and nutritional security and healthy lives.  See all the posters.

 

Over 60% of the newly identified infectious diseases that have affected people over the past few decades have been caused by pathogens originating from animals or animal products.

In agricultural areas that use more water, people face increased risk of infectious diseases, especially through zoonotic diseases (diseases transmissible from animals to people) as well as water-borne and vector-borne diseases.

The CGIAR Research Program on Agriculture for Nutrition and Health (A4NH) carries out research to maximise the nutritional and health benefits of agricultural development. The programme has four research themes: value chains, biofortification, control of agriculture-associated diseases, and integrated programs and policies.

The poster below, prepared for the Tropentag 2014 conference, presents an overview of a research carried out by the International Livestock Research Institute (ILRI), which leads the research theme on the prevention and control of agriculture-associated diseases within A4NH.

This research theme generates evidence on the prevalence, dynamics and burdens of agriculture-associated diseases by developing and testing the tools and approaches needed to better manage such diseases.

.

Managing the health risks associated with agriculture: An overview of research by the International Livestock Research Institute

This week, ILRI staff are participating in the Tropentag 2014 International Conference in Prague, Czech Republic (17-19 September 2014). There is also a dedicated ILRI@40 side event on livestock-based options for sustainable food and nutritional security and healthy lives.  See all the posters.

Emerging and neglected zoonoses have often been managed sectorally, but recent decades have shown, in case after case, the benefits of One Health management.

The growing body of evidence suggests the time has come to make the bigger case for massive investment in One Health to transform the management of neglected and emerging zoonoses, annually saving the lives of millions of people as well as hundreds of millions of animals whose production supports and nourishes billions of impoverished people.

Delia Grace, a veterinary epidemiologist and food safety expert at the International Livestock Research Institute (ILRI) sets out a ‘Big 5’ framework for One Health:

  1. Join up health resources: Share health resources across human and veterinary sectors
  2. Control zoonoses in animal reservoirs
  3. Detect disease outbreaks early
  4. Prevent pandemics
  5. Add value to health research and development

Read the full post on the CGIAR Development Dialogues blog

Read an earlier full version of this story on the ILRI News blog

Local breed sow and piglets on a farm in Masaka district, Uganda

Local breed sow and piglets on a farm in Masaka district, Uganda. A new research report assesses the risk of Ebola in the pig value chain in Uganda. (photo credit: ILRI/Eliza Smith).

Scientists from the International Livestock Research Institute (ILRI) have published a report of a risk assessment to determine the threat of the deadly Ebola virus in the pig value chain in Uganda.

Uganda is currently witnessing a rise in demand for pork and this has led to increased pig production in the country, mostly under smallholder production systems.

These higher pig populations raised under free-range or tethering systems may create overlap of fruit bat habitats where the pigs scavenge for food, thereby presenting a possible risk of Ebola transmission as some bat species have been identified as reservoir hosts of the Ebola virus.

Uganda has experienced outbreaks of Ebola virus disease in the past. However, there are still many unanswered questions on the ecology and mode of transmission of the Ebola virus.

The risk assessment study, based on a systematic review of literature, identified possible routes of transmission of the Ebola virus if pigs are involved, for example, spread between wild and domestic pigs, direct contact between infected pigs and humans, and contact between pigs and fruit bats.

The study recommends more research on the possible role of pigs in Ebolavirus transmission, an area that is not well understood at the moment.

“The present data suggest that pigs may act as amplifying hosts, but likely not reservoir hosts. This suggests the conditions under which pigs become infected with Ebolavirus and the role they play in transmission may have many variables that will have to be elucidated,” the report states.

Further research is underway to investigate the possible role of domestic pigs in the ecology of Ebola virus in Uganda and understand the public health significance of the virus to the pig value chain in this country.

The work includes laboratory diagnostics from a large sample of blood from domestic pigs collected as part of the initial wider value chain disease assessment.

This will be accompanied by a risk mapping study using spatial epidemiology and key informant surveys as well as some participatory techniques with key stakeholders to better understand risk factors and to serve as a ‘ground-truthing’ exercise for the risk map.

It is hoped that this research will lead to further collaborations with other public health organizations and serve as a potential predictive tool in the event of future outbreaks of Ebola in Uganda.

Access the research report here

Citation
Atherstone C, Roesel K and Grace D. 2014. Ebola risk assessment in the pig value chain in Uganda. ILRI Research Report 34. Nairobi, Kenya: ILRI.

ILRI Clippings

Feeding poultry, Bangladesh. Photo by WorldFish, 2006

Feeding poultry in Bangladesh (photo on Flickr by WorldFish).

A recent paper that maps the global distributions of the world’s major livestock species has already been used to advance understanding of where surveillance efforts should be targeted to prevent the possible spread of a lethal bird flu virus now circulating in poultry populations in China, where it has killed 62 people. The original mapping work, led by Tim Robinson, of the International Livestock Research Institute (ILRI), and published at the end of May, was immediately put to practical use in locating large regions in South and Southeast Asia that would suit the new lethal virus. Ominously, unlike H5N1, a viral strain of bird flu that has killed millions of poultry and at least 359 humans since its first appearance in 1987, H7N9 does not cause severe illness in the chickens it infects, making it much more difficult to detect, and…

View original post 782 more words

Farming in the highlands of Ethiopia

Livestock farming in the highlands of Ethiopia (photo credit: ILRI/Apollo Habtamu).

One Health refers to the collaborative effort of multiple disciplines to attain optimal health for people, animals and the environment. Although the usefulness of the One Health approach is widely appreciated, thanks to a growing body of evidence, its uptake remains limited and health management is still largely organized by sector.

How, then, can One Health proponents build a compelling business case for it? A new article published in the Onderstepoort Journal of Veterinary Research (23 April 2014) may be of help; it outlines a pathway to develop the business case for One Health.

It also identifies five key areas where One Health is likely to make a difference. These are:

  1. sharing health resources between the medical and veterinary sectors;
  2. controlling zoonotic diseases in animal reservoirs;
  3. early detection of and response to emerging diseases;
  4. prevention of pandemics; and
  5. generating insights and adding value to health research and development.

The literature reviewed suggests that every dollar invested in One Health would yield five dollars worth of benefits. Therefore, increased investment in One Health on a large scale has the potential to transform the management of emerging and neglected zoonotic diseases and save the lives of millions of people and animals.

The article is authored by Delia Grace, veterinary epidemiologist and food safety specialist at the International Livestock Research Institute (ILRI). She heads ILRI’s research program on food safety and zoonoses as well as the agriculture-associated diseases theme of the CGIAR Research Program on Agriculture for Nutrition and Health (A4NH).

Access the article here

Citation
Grace D. 2014. The business case for One Health. Onderstepoort Journal of Veterinary Research 81(2), 6 pages.

 

Pig production is an important livelihood activity for some 1 million smallholder households in Uganda, given the growing demand for pork in both rural and urban areas.

However, many smallholder pig farmers are constrained by lack of adequate information on animal health, feeding and breeding that can help them improve their pig husbandry and scale up their operations towards commercialized production and greater profits.

Pig Production and Marketing Uganda Limited works with pig farmers – from smallholder to large-scale – to increase productivity and create a reliable market for pig farm produce. The organization also offers technical support to pig farmers in Uganda.

As part of its efforts towards improving pig husbandry in Uganda, the organization held a training workshop on 14-15 February 2014 in Matugga, Wakiso District for some 70 farmers.

The aim of the workshop was to share knowledge on modern pig farming methods and good agricultural practices in pig husbandry. Other topics included feeding, breeding, pig health, management of pig diseases, farm management and record keeping.

Scientists from the International Livestock Research Institute (ILRI) were invited to participate in the workshop as part of the team of facilitators.

Danilo Pezo, coordinator an ILRI project on smallholder pig value chain development in Uganda, gave the opening address. Kristina Roesel, coordinator of the ILRI-led Safe Food, Fair Food project, facilitated a session on pig and pork zoonoses in Uganda.

.

The event received media coverage in the Daily Monitor newspaper (Piggery: Farmers urged on best practices, 19 Feb 2014)

Related blog post: Ugandans and pork: A story that needs telling (ILRI News blog, 19 Feb 2014)

We are pleased to congratulate Elizabeth Cook, a graduate fellow at the International Livestock Research Institute (ILRI) with the Zoonotic and Emerging Diseases research group, who won third prize in a poster competition held to commemorate 100 years since the founding of the UK Medical Research Council (MRC).

The MRC centenary celebration took place at the Royal Society, London on 10 December 2013 at a high-level event that brought together various heads of international biomedical research organizations, experienced researchers, parliamentarians and international research administrators and funders.

The poster competition had been organized for MRC-funded early-career researchers to communicate how international collaboration has been pivotal to their research. Cook’s PhD studentship at the University of Edinburgh is funded by the MRC.

Her poster, International partnerships – Shining the light on the neglected zoonoses, featured the People, Animals and their Zoonoses project which investigates zoonoses in western Kenya towards developing appropriate interventions for disease prevention and control.

The coordinating partners in the project are the University of Edinburgh, the Kenya Medical Research Institute, Kenya’s Department of Veterinary Services and ILRI.

The project also works in partnership with a number of universities and research institutes across the world for sampling, diagnostics and data analysis.

Funding for the project is from the Wellcome Trust and the CGIAR Research Program on Agriculture for Nutrition and Health (A4NH).

Morning milking in Rajasthan, India

Morning milking in Rajasthan, India. Regional experts have called for appropriate One Health approaches to improve the prevention and control of zoonoses and agriculture-associated diseases in South Asia (photo credit: ILRI/Susan MacMillan).

On 25 November 2013, a regional multi-stakeholder forum on One Health/Ecohealth, with special emphasis on agriculture-associated diseases, was held in New Delhi, India. The event brought together some 50 high-level representatives from the human, animal and environmental health sectors, including international donors, policymakers, developmental agencies and researchers.

Among the several issues discussed was the need for a centralized body or coordination mechanism to address the prevention and control of zoonotic diseases in the South Asia region. With regard to disease surveillance and reporting, it was felt that in countries like India which follow a ‘top-down’ approach, there is need to also incorporate community-based ‘bottom-up’ surveillance that focuses not just on reporting but also on development.

Several participants drew attention to the need to develop robust estimates on how much zoonotic diseases are currently costing the public and private sectors. In order to be able to convince policymakers to invest in One Health, there is need to provide estimates of the full cost of disease and the cost of different options for reducing it.

One of the suggestions put forward to add value to One Health efforts was to document best practices – with clear pointers to what worked well and what did not – and share these lessons with states and regions who could adapt them to suit their local contexts. This is important as because there is no ‘one size fits all’ approach to One Health.

The stakeholder forum was organized by the South Asia office of the International Livestock Research Institute (ILRI) and supported by the International Association for Ecology and Health, the CGIAR Research Program on Agriculture for Nutrition and Health (A4NH) and the Public Health Foundation of India.

Access the workshop report

« Previous PageNext Page »